Codeine continues to be described to show no proof of carcinogenicity or mutagenicity in many different take a look at systems, such as the micronucleus and sperm abnormality assays as well as the Salmonella assay. Promethazine was nonmutagenic while in the Salmonella check system of Ames.benzhydrocodone/acetaminophen and promethazine both of those